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Category Archive for: ‘News Editorial’

  • The Benefits of Entrusting Your Histopathology Services to EPL

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    Companies who outsource the histopathology component of their valuable studies need to know that the work will be performed to the highest quality standards, on time, and at competitive prices.  Although claims of quality are easily made, true quality can be a difficult metric to …

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  • Blindpath

    A Further Look at Blind Slide Reading

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    In toxicologic pathology, “blind slide reading” involves procedures in which the pathologist is unaware of the treatment group status of individual animals during the histologic slide evaluation phase of a toxicologic bioassay.  Blind slide reading continues to be a controversial topic, despite published recommendations on …

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  • Aclairo PDG

    Meet Aclairo Pharmaceutical Development Group

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    Imagine a group of great scientists and all around nice folks who worked with another group for years in dovetailed projects for their clients. It does not take much imagination to wonder why these folks would want to be in one happy group together.  On …

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  • Hourglass3

    On-Time Pathology Reporting

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    It is every client’s desire and expectation that their study report will be completed “On-Time” or better yet, be available ahead of schedule. There are a number of factors that determine whether a pathology report will be early, on time, or in the worst case …

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  • 3rd Annual Short Course on Toxicologic Pathology in Fish. October 7-9, 2015. Centre for Fish and Wildlife Health at the University of Bern, Switzerland

    EPL CSO Teaches at 3rd Annual Short Course on Toxicologic Pathology in Fish

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    From October 7-9, 2015, Jeff Wolf, EPL CSO and Manager of Pathology at the Virginia Laboratory, participated as a faculty member at the third annual “Short Course on Toxicologic Pathology in Fish” held at the Centre for Fish and Wildlife Health at the University of …

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  • PancreaticDuct.Normal

    Histology Slide Quality

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    A quality histological slide contains tissue that was properly sampled, fixed, processed, embedded, microtomed, and stained without artifacts. The production of a quality slide requires that work be conducted according to the highest standards during each phase of histologic processing. The first and most important …

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  • EPL-VA Histology Laboratory

    Expedited Scheduling of Histology and Histopathology

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    In today’s drug development environment, many of our clients have critical projects with tight timelines that need to be met in order to advance their programs.  This is particularly vital in the pre-IND (Investigational New Drug) phase of a preclinical drug development program.  Often, expedited …

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  • Drug-induced Vascular Injury (DIVI): An Often Complicated Issue

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    Drug-induced vascular injury (DIVI) is a major concern for development of new and novel therapies.  Efforts to identify biomarkers consistent with DIVI have not been successful, largely attributed to the complex nature of the vascular responses to injury and a lack of understanding of the …

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  • Quantitation of aberrant cell nuclei and mitotic figures in Feulgen’s stained sections of mouse duodenum via image analysis.

    Evolving Roles of the Toxicologic Pathologist in Multi-disciplinary Research

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    The role of the toxicologic pathologist is continuously evolving and becoming ever more complex, as novel tools are being developed to identify structural and biochemical changes that result from exposure to toxic substances, and elucidate mechanisms of action by which toxins may potentially impact animal …

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  • Fathead Minnow Fish Pimephales Promelas W725 H456

    EPL Pathologists Attend Workshop on Aquatic Models and 21st Century Toxicology

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    Dr. Jeffrey Wolf and Dr. Torrie Crabbs attended the “Collaborative Workshop on Aquatic Models and 21st Century Toxicology” on May 5-6, 2014 at the James B. Hunt Jr. Library at North Carolina State University’s Centennial Campus in Raleigh, NC.  The meeting was the result of …

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