Blog

Another Award from The Society of Toxicologic Pathology!!

0

Congratulations to Dr. Jeff Wolf who was first author of an article that was selected at the Society of Toxicologic Pathology 2016 Annual Symposia as the Best Reviewed Paper in Toxicologic Pathology!

This is quite an accomplishment considering the many exceptional articles submitted to the journal in the past year.

The article can be found at:  http://www.ncbi.nlm.nih.gov/pubmed/25112278.

 

Nonlesions, misdiagnoses, missed diagnoses, and other interpretive challenges in fish histopathology studies: a guide for investigators, authors, reviewers, and readers.

Toxicol Pathol. 2015 Apr;43(3):297-325. doi: 10.1177/0192623314540229. Epub 2014 Aug 11.

Wolf JC1, Baumgartner WA2, Blazer VS3, Camus AC4, Engelhardt JA5, Fournie JW6, Frasca S Jr7, Groman DB8, Kent ML9, Khoo LH10, Law JM11, Lombardini ED12, Ruehl-Fehlert C13, Segner HE14, Smith SA15, Spitsbergen JM16, Weber K17, Wolfe MJ18.

1Experimental Pathology Laboratories, Inc., Sterling, Virginia, USA jwolf@epl-inc.com.

2Department of Pathobiology/Population Medicine, College of Veterinary Medicine, Mississippi, USA.

3U.S. Geological Survey, Kearneysville, West Virginia, USA.

4Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.

5Experimental Pathology Laboratories, Inc., Camarillo, California, USA.

6U.S. Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Gulf Ecology Division, Gulf Breeze, Florida, USA.

7Connecticut Veterinary Medical Diagnostic Laboratory, Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut, USA.

8Aquatic Diagnostic Services, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada.

9Departments Microbiology & Biomedical Sciences, Oregon State University, Corvallis, Oregon, USA.

10Mississippi State University, College of Veterinary Medicine, Stoneville, Mississippi, USA.

11Aquatic Ecotoxicology, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.

12Divisions of Comparative Pathology and Veterinary Medical Research Department of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand.

13Bayer HealthCare AG, Wuppertal, Germany.

14Centre for Fish and Wildlife Health, University of Bern, Bern, Switzerland.

15Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia, USA.

16Fish Disease Research Group, Department of Microbiology, Oregon State University, Corvallis, Oregon, USA.

17AnaPath GmbH, Oberbuchsiten, Switzerland.

18Experimental Pathology Laboratories, Inc., Sterling, Virginia, USA.

Abstract

Differentiating salient histopathologic changes from normal anatomic features or tissue artifacts can be decidedly challenging, especially for the novice fish pathologist. As a consequence, findings of questionable accuracy may be reported inadvertently, and the potential negative impacts of publishing inaccurate histopathologic interpretations are not always fully appreciated. The objectives of this article are to illustrate a number of specific morphologic findings in commonly examined fish tissues (e.g., gills, liver, kidney, and gonads) that are frequently either misdiagnosed or underdiagnosed, and to address related issues involving the interpretation of histopathologic data. To enhance the utility of this article as a guide, photomicrographs of normal and abnormal specimens are presented. General recommendations for generating and publishing results from histopathology studies are additionally provided. It is hoped that the furnished information will be a useful resource for manuscript generation, by helping authors, reviewers, and readers to critically assess fish histopathologic data.

 

Share This:Share on FacebookTweet about this on TwitterShare on LinkedInShare on Google+Pin on PinterestEmail this to someone

Leave a Reply