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EPL Activities at the 35th American College of Toxicology (ACT) Annual Meeting

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EPL is pleased to announce that we will be exhibiting at the 35th American College of Toxicology (ACT) Annual Meeting in Orlando, FL.  Please visit us this year at Booth #306.

EPL will be sponsoring three Continuing Education Courses and two Symposia during the meeting this year.

EPL is co-sponsoring a CE Course along with VPS, Inc entitled, “Best Practices in Toxicologic Pathology,” to be held Sunday, November 9, 2014 from 8:00am – 11:30am.  This session will address guidance documents dealing with organ systems and tissues that require unique approaches for evaluation.  The guidance documents that have been selected are those that deal with basic issues in study design and interpretation that toxicologists and pathologists can use in their conduct and reporting of toxicity studies.

EPL is also co-sponsoring a CE Course along with Gad Consulting Services entitled, “QSAR – A Tool for the Toxicologist,” to be held Sunday, November 9, 2014 from 1:00pm – 4:30pm.  Dr. Tom Steinbach of EPL will serve as a Chairperson.  This session will discuss (Quantitative) Structure-Activity Relationships [(Q)SAR] methodologies which use predictive computer modeling based on pre-defined rules or statistical tools to correlate biologic activity with the molecular structure or properties of a compound. (Q)SAR has applications in risk assessment, drug discovery, and regulatory decision making. This session will cover, from a toxicologist’s perspective, how to interpret (Q)SAR results; how regulatory agencies use and interpret (Q)SAR; practical applications of (Q)SAR in toxicology; and potential future application of (Q)SAR.

Additionally, Dr. Torrie Crabbs from EPL will serve as a Chairperson for the CE Course, “Toxicology and Pathology of the Respiratory System.”  EPL is also co-sponsoring this session along with WIL Research Laboratories, LLC.  This session will take place on Sunday, November 9, 2014 from 1:00pm – 4:30pm and will present an overview of the respiratory tract and discuss the toxicological significance of effects in the nose, larynx, trachea, and lung. Basic structure and function of these tissues from common laboratory species will be discussed along with protocol design for inhalation toxicology studies, current methods for evaluating respiratory structures and function, biomarkers, different tools used to determine treatment-related effects, and spontaneous and induced changes observed in each part of the respiratory tract.  As part of this session, Dr. Crabbs will be giving a presentation titled, “Anatomy and Toxicologic Pathology of the Upper and Lower Respiratory Tract.”

Additional information about the CE Courses offered at the 2014 ACT Annual Meeting can be found at the American College of Toxicology website.

EPL is co-sponsoring a symposium along with BASi entitled, “Differentiating Adverse from Adaptive Changes in Toxicology.”  This session will be held on Tuesday, November 11, 2014 from 2:00pm – 5:00pm.  Dr. Arun Pandiri from EPL will be serving as Co-chair for the Symposium which will ask “what is an adverse finding?”  This symposium will explore what adverse findings are and what differentiates them from normal physiological or adaptive changes from whole-animal, organ, molecular, and regulatory perspectives.  As part of this session, Dr. Peter Mann will be giving a presentation titled, “Adversity in Toxicology Studies – an Introduction.”

Dr. Kathleen Funk from EPL will be serving as Chair for the Symposium, “Stem Cells Research.”  This session will be held on Wednesday, November 12, 2014 from 9:00am – 12:00pm.  EPL will be co-sponsoring this symposium along with Preclinical Research Services.  This symposium will provide an overview of the state of the stem cell research as it related to toxicology, stem cell models, allogeneic stem cell treatments and issues of immunogenicity associated with protein therapeutics.  Also discussed will be the uses of stem cells in regenerative medicine focusing on lung and testing strategies on engineered tissues from a pathologist’s’ perspective.

Additional information about the Symposia to be held at the 2014 ACT Annual Meeting can be found at the American College of Toxicology website.

Dr. Arun Pandiri will also be presenting a poster titled, “MicroRNA Profiling of Hepatocellular Carcinomas in B6C3F1 Mice Treated with Ginkgo biloba Extract by Gavage for 2 Years.”

For more information about all activities for the ACT 2014 Annual Meeting, please visit www.actox.org.

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